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NDT Advance Access originally published online on March 20, 2008
Nephrology Dialysis Transplantation 2008 23(6):1819-1822; doi:10.1093/ndt/gfn125
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© The Author [2008]. The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions@oxfordjournals.org


Environmental prevention of human disease from verocytotoxin-producing Escherichia coli

Reena Khanna1, Laurie Waechter2, Jan Sargeant3, William F. Clark2 and Amit X. Garg2,4

1 Department of Internal Medicine 2 Division of Nephrology, University of Western Ontario, London 3 Centre for Public Health and Zoonoses, Guelph 4 Department of Epidemiology and Biostatistics, University of Western Ontario, London, Ontario, Canada

Correspondence and offprint requests to: Amit Garg, London Kidney Clinical Research Unit, Room ELL-101, Westminster, London Health Sciences Centre, 800 Commissioners Road East, London, Ontario N6A 4G5, Canada. Tel: +1-519-685-8502; Fax: +1-519-685-8072; E-mail: amit.garg{at}lhsc.on.ca



  Abstract

Verocytotoxin-producing Escherichia coli (VTEC) haemolytic uraemic syndrome (HUS) is an important cause of mortality and renal failure worldwide. For those patients who need medical attention, no treatment aside from supportive care has proven effective for this disease. This has prompted a broader look at environmental prevention, with a particular emphasis on the transmission of bacteria from animal carriers to human beings. Here, we review animal- and meat-handling strategies to reduce the burden of VTEC human disease.

Received for publication: 4. 9.07
Accepted in revised form: 13. 2.08


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