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Nephrology Dialysis Transplantation 2007 22(Supplement 7):vii78-vii104; doi:10.1093/ndt/gfm332
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© The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Management of anaemia in haemodialysis and peritoneal dialysis patients (Chapter 8)

Donald Richardson1, Alex Hodsman2, Dirk van Schalkwyk2, Charlie Tomson2 and Graham Warwick3

1Consultant Nephrologist, York NHS Hospitals Trust, York UK, 2UK Renal Registry, Bristol and 3Leicester General Hospital, Leicester

Correspondence and offprint requests to: Donald Richardson, Consultant Nephrologist, York NHS Hospitals Trust, York UK. Email: donald.richardson{at}york.nhs.uk



  Abstract

Forty-one percent of UK patients commence RRT with an Hb <10.0 g/dl. The mean Hb at commencement of RRT is 10.3 g/dl. Eighty-five percent of patients on dialysis in the UK have an Hb ≥ 10.0 g/dl by 6 months after commencement of RRT.

The median Hb on haemodialysis in the UK is 11.8 g/dl with an IQR of 10.7–12.8 g/dl. Eighty-six percent of haemodialysis patients in the UK have a Hb ≥ 10.0 g/dl. The median Hb on peritoneal dialysis in the UK is 12.0 g/dl with an IQR of 11.0–12.9 g/dl. Ninety percent of peritoneal dialysis patients in the UK have an Hb ≥ 10.0 g/dl.

In the UK, 49% of patients on PD and 48% of patients on haemodialysis have an Hb between 10.5–12.5 g/dl.

The median ferritin in UK haemodialysis patients is 413 µg/l (IQR 262–623), 95% of UK haemodialysis patients have a ferritin ≥100 µg/l.

The median ferritin in UK PD patients is 256 µg/l (IQR 147–421), 86% of UK peritoneal dialysis patients have a ferritin ≥ 100 µg/l.

A higher proportion of HD patients than PD patients receive ESA therapy (88% vs 76%). The ESA dose is higher for HD than PD patients (9204 vs 6080 IU/week).

Keywords: anaemia; chronic kidney disease; dialysis; end stage renal disease; epidemiology; erythropoietin; ferritin; haemoglobin; quality improvement; renal registry


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