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Nephrology Dialysis Transplantation 2007 22(Supplement 7):vii176-vii180; doi:10.1093/ndt/gfm337
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© The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Growth in children with established renal failure—a Registry analysis (Chapter 14)

Malcolm Lewis1, Joanne Shaw1, Chris Reid2, Jonathan Evans3, Nicholas Webb1 and Kate Verrier-Jones4

1Central Manchester & Manchester Childrens University Hospitals NHS Trust, 2Guys and St Thomas's; NHS Foundation Trust, 3Nottingham University Hospitals NHS Trust and 4University Hospital of South Wales NHS Trust

Correspondence and offprint requests to: Dr Malcolm A Lewis, Renal Office, Royal Manchester Children's; Hospital, Hospital Road, Pendlebury, Manchester M27 4HA, UK. Email: malcolm.lewis{at}cmmc.nhs.uk



  Abstract

Short stature is a major problem in paediatric ERF patients with 29% of transplant patients and 41% of dialysis patients below the second percentile for height. Only 6.5% of transplant patients and 15.5% of dialysis patients are receiving rhGH. There is no significant difference in the height distribution of patients commencing RRT and those who have had a functioning allograft for at least 1 year. In patients with at least 2 years between presentation and RRT, there is a significant fall in height Z score. This overall statistic is strongly influenced by the very poor growth of patients with glomerular disease.

Keywords: chronic kidney disease; dialysis; end stage renal disease; epidemiology; ERF; established renal failure; growth; growth hormone; RhGH; transplantation


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