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Nephrology Dialysis Transplantation 2006 21(Supplement 2):ii38-ii41; doi:10.1093/ndt/gfl189
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© The Author [2006]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Peritoneal sclerosis—aetiology, diagnosis, treatment and prevention

Trijntje T. Cnossen1, Constantijn J. A. M. Konings1, Jeroen P. Kooman2 and Bengt Lindholm3

1 Department of Internal Medicine, Catharina Hospital Eindhoven, 2 Department of Nephrology, University Hospital Maastricht, The Netherlands and 3 Divisions of Baxter Novum and Renal Medicine, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden

Correspondence and offprint requests to: C. J. A. M. Konings MD, PhD, Catharina Ziekenhuis, Michelangelolaan 2, 5623 EJ EINDHOVEN, The Netherlands. Email: intskg{at}cze.nl

Peritoneal selerosis (PS) is a rare, but potentially life-threatening complication in peritoneal dialysis (PD). The annual incidence increases with the duration of PD treatment and the mortality rate is high. Aetiology of PS is probably multifactorial and in most cases not exactly known. One import factor of PS is the bioincompatibility of the glucose-based PD solutions. Diagnosis is mainly based on clinical suspicion and radiological findings. Early detection is important to institute preventive strategies and development of therapeutic strategies has reduced mortality.


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