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Nephrology Dialysis Transplantation 2006 21(Supplement 2):ii16-ii19; doi:10.1093/ndt/gfl186
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© The Author [2006]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Estimates of peritoneal membrane function—new insights

Watske Smit

Department of Nephrology, Academic Medical Center, Amsterdam, The Netherlands

Correspondence and offprint requests to: Watske Smit, MD, PhD, Department of Medicine, Renal Unit, F4-222, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 ED Amsterdam, The Netherlands. Email: Wa.Smit{at}amc.nl

The most widely used peritoneal function test is the peritoneal equilibration test (PET), developed and described by Twardowski in 1987. The test was originally performed using a 2.27% glucose solution and focused on transport of small solutes. With the test, categorization of patients was possible into high, average and low transporters. However, to detect clinically significant ultrafiltration failure and to make an evaluation of the cause, the International Society for Peritoneal Dialysis (ISPD) committee on ultrafiltration failure advised to perform the test with a 3.86% glucose solution. Since then, reference values for this test were assessed and further possibilities of utilizing the results were tested. In this review, the new developments in monitoring peritoneal function are described and a guideline proposal for this monitoring is given.

Keywords: free water transport; peritoneal transport; PET; reference values


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