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NDT Advance Access originally published online on September 8, 2006
Nephrology Dialysis Transplantation 2006 21(11):3223-3230; doi:10.1093/ndt/gfl392
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© The Author [2006]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Mental health at the third month of haemodialysis as a predictor of short-term survival

Covadonga Valdés1, Mónica García-Mendoza1, Pablo Rebollo2, Teresa Ortega1 and Francisco Ortega1

1Nephrology Unit, Hospital Universitario Central de Asturias and 2BAP HEALTH OUTCOMES, Asturias, Spain

Correspondence and offprint requests to: Covadonga Valdés, Departamento Técnico Instituto Nacional de Silicosis, C/Manuel Bellmunt sn 33006 Oviedo, Asturias, Spain. Email: cvaldes{at}hca.es

Background. The aim of this study was to evaluate the survival of patients initiating haemodialysis (HD), and to analyse whether low health-related quality of life (HRQoL) levels are predictors of mortality in the short-term, controlling certain variables that had been shown in other studies to have a bearing on survival, and using scores, standardized for age and sex, of the HRQoL measurement tool employed.

Methods. This is a multicentric prospective study of all patients on HD in all the dialysis units in Asturias, a region with a little over one million inhabitants, from 1 January 2001 to 30 September 2002. A total of 199 patients initiated HD in our region and survived the first 3 months. Of these, 137 patients who remained on HD for at least 3 months had complete responses on HRQoL measures.

Results. It was observed that adjusted relative risk (RR) of death increased by 5% for each year of age increase (RR = 1.05, 95% CI 1.01–1.09: P = 0.006); in the same way, for each increase in the Mental Component Summary (MCS) score, the adjusted RR of death diminished by 4% (RR = 0.96, 95% CI 0.94–0.99; P = 0.006).

Conclusion. Mental health has been shown to be a factor independently associated with mortality; as the MCS score worsens the adjusted RR of death of a patient on HD increases.

Keywords: elderly; end-stage renal disease; health-related quality of life, mortality; survival


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