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Nephrol Dial Transplant (2003) 18: III31-III33
© 2003 European Renal Association-European Dialysis and Transplant Association

Original Article

Guidelines for percutaneous ethanol injection therapy of the parathyroid glands in chronic dialysis patients

Masafumi Fukagawa, Masafumi Kitaoka, Yoshihiro Tominaga, Tadao Akizawa, Takatoshi Kakuta, Noritaka Onoda, Fumihiko Koiwa, Shigeru Yumita and Kiyoshi Kurokawa for the Japanese Society for Parathyroid Intervention

Percutaneous ethanol injection therapy (PEIT) of the parathyroid was originally introduced as an alternative to surgical parathyroidectomy. After the recent elucidation of the pathogenesis of parathyroid hyperplasia in uraemia, ‘selective PEIT of the parathyroid glands' was developed, in which enlarged parathyroid glands with nodular hyperplasia are ‘selectively’ destroyed by ethanol injection, and other glands with diffuse hyperplasia are then managed by medical therapy. The ‘Guidelines for percutaneous ethanol injection therapy of the parathyroid glands in chronic dialysis patients' proposed by the Japanese Society for Parathyroid Intervention are presented, including indications, techniques, and post-PEIT management. These guidelines also apply to direct injection therapy using drugs other than ethanol, such as calcitriol and 22-oxacalcitriol.

Keywords: secondary hyperparathyroidism; percutaneous ethanol injection therapy (PEIT); ultrasonography; nodular hyperplasia

Correspondence and offprint requests to: Masafumi Fukagawa, MD, PhD, FJSIM, Associate Professor and Director, Division of Nephrology and Dialysis Center, Kobe University School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan. Email: fukagawa{at}med.kobe-u.ac.jp


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