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Nephrol Dial Transplant (2002) 17: 62-64
© 2002 European Renal Association-European Dialysis and Transplant Association

Genes and Development

Using bioinformatics to identify kidney genes

Jonathan B. L. Bard

Department of Biomedical Sciences, Edinburgh University, Edinburgh EH8 9XD, UK

Abstract

Online knowledge of genes involved in mouse kidney development is available from the literature (PubMed) and text-based (Kidney Development and Mouse Gene Expression—GXD) databases. Further information is in gene databases of other organisms having tissues homologous to the metanephros (e.g. Drosophila Malpighian tubules; tools are available for identifying mouse homologues of non-mouse genes) and from tissues homologous to those in the developing kidney (e.g. mesothelium that, like nephrons, arises from a mesenchyme to epithelial transition). Future databases will also include graphical data, and this knowledge will provide a further level of insight. These databases and tools are discussed here.

Keywords: kidney genes; web-accessible databases

Notes

Correspondence and offprint requests to: Jonathan B. L. Bard, Department of Biomedical Sciences, Edinburgh University, Edinburgh EH8 9XD, UK.


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