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Nephrol Dial Transplant (2002) 17: 50-51
© 2002 European Renal Association-European Dialysis and Transplant Association

SECTION IV: Dialysis fluid purity

IV.5 Electrolytic concentrates

Abstract

Electrolytic concentrates are required for the preparation of the dialysis fluid. Originally liquid electrolyte concentrates provided in two independent plastic containers (A for acid; B for bicarbonate) were extemporaneously reconstituted into dialysis fluid by the dialysis machine. Nowadays, bicarbonate is mainly distributed as a soluble powder, which is diluted to a saturated solution by the dialysis machine. Concentrates may be the source of bacterial dialysis fluid contamination, particularly the bicarbonate solution, which is an excellent medium for bacterial growth [66]. Salts used in the preparation of concentrate may as well be the source of metal intoxication [67].

Guideline IV.5

A. Bicarbonate concentrate must be handled with care to prevent bacterial contamination after container opening. The use of already open containers should be discouraged.

(Evidence level: C)


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