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Nephrol Dial Transplant (2002) 17: 86-92
© 2002 European Renal Association-European Dialysis and Transplant Association

Health profiles and health preferences of dialysis patients

G. Ardine de Wit1,, Maruschka P. Merkus2, Raymond T. Krediet3 and Frank Th. de Charro4

1 Sanders Institute, Erasmus University Rotterdam, and National Institute of Public Health and the Environment, Bilthoven, 2 Department of Clinical Epidemiology and Biostatistics, Academic Medical Centre, Amsterdam, 3 Renal Unit, Department of Medicine, Academic Medical Centre, Amsterdam and 4 Renal Replacement Registry of the Netherlands (Renine), Rotterdam, The Netherlands

Background. Health-related quality of life (HRQOL) of haemodialysis (HD) and peritoneal dialysis (PD) patients has been assessed with health profiles and health preferences methods. Few studies have used both types of HRQOL instruments. The main objective of this study was to assess the relationship between information from the two types of HRQOL instruments in dialysis patients.

Methods. We interviewed 135 patients, using two health profiles (Short Form 36 and EuroQol/EQ-5D) and two health preferences methods (Standard Gamble and Time Trade Off). Socio-demographic, clinical, and treatment-related background data were collected from patient charts and during the interview. Relationships between the outcome measures were assessed with Pearson correlation coefficients. Multiple regression models were used to study the relationship of HRQOL outcomes to background variables.

Results. The HRQOL of dialysis patients as measured with health profiles was severely impaired. The health preferences scores were higher (0.82–0.89) than scores previously reported in the literature. Correlations between health profiles and health preferences were poor to modest. HRQOL outcomes were poorly explained by background characteristics. Differences between HD and PD groups could not be demonstrated.

Conclusions. Health profiles and health preferences represent different aspects of HRQOL. An impaired health status may not be reflected in the preference scores. Coping strategies and other attitudes towards health may affect the preference scores more than they influence health profile outcomes. The added value of health preferences methods in clinical research is limited.

Keywords: haemodialysis; health-related quality of life; health status; peritoneal dialysis; preference measurements

Correspondence and offprint requests to: G. A. de Wit, National Institute of Public Health and Environment (RIVM), Department for Health Services Research CZO, PO Box 1, NL-3720 BA Bilthoven, The Netherlands. Email: ardine.de.wit{at}rivm.nl


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