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Nephrol Dial Transplant (2002) 17: 28-32
© 2002 European Renal Association-European Dialysis and Transplant Association


Dialysis and Transplantation News

The epidemiology of end-stage renal disease in Iran in an international perspective

Ali Nobakht Haghighi1, Behrooz Broumand2, Marco D'Amico3, Francesco Locatelli3, and Eberhard Ritz4

1 Taleghani University Hospital, Shahid Beheshti Medical Sciences University, Tehran, Iran, 2 Rasoul Akram University Hospital, University of Medical Sciences of Iran, Tehran, Iran, 3 Azienda Ospedale di Lecco, A. Manzoni Hospital, Lecco, Italy and 4 Department of Nephrology, University of Heidelberg, Heidelberg, Germany

Abstract

Introduction. The epidemiology of end-stage renal disease (ESRD) and renal replacement therapy (RRT) is under continuous evolution all over the world. We report here the epidemiological analysis of ESRD and RRT in Iran and discuss it against the background of the international situation.

Methods. This epidemiological report is based on data from centre questionnaires which were collected in Iran from 1997 onwards, with a response rate of 100%.

Results. The prevalence/incidence of RRT patients were 238/49.9 p.m.p. in the year 2000. Haemodialysis and kidney transplantation were the most common RRT modalities, accounting for 53.7% and 45.5% of prevalent RRT patients, respectively. The proportion treated by peritoneal dialysis was very low (<1%). Home haemodialysis was not performed. The majority of haemodialysis centres used synthetic membranes (70%) and 100% of the sessions were performed using acetate as a buffer; 42.5% of haemodialysis patients were treated with a twice-weekly regimen, whilst 49.6% were on the standard thrice-weekly regimen. The majority of RRT patients in Iran were young to middle aged. The great majority of renal allografts came from living donors (mainly unrelated to recipients). The main renal diseases leading to ESRD were diabetes and hypertension. The third most common category was ‘cause unknown’.

Conclusion. The epidemiology of RRT in Iran is characterized by: (i) young patient age (younger than the international average); (ii) high proportion of patients receiving renal allograft; (iii) use of living-unrelated donors as the major source of renal allografts.

Notes

* Data of the Dialysis and Transplantation Symposium Joint Meeting, Tehran, 28–30 April 2001.

Correspondence and offprint requests to: Prof. Dr Francesco Locatelli, Department of Nephrology and Dialysis, Ospedale A. Manzoni, Via Dell'Eremo 9/11, I-23900 Lecco, Italy. Email: nefrologia{at}ospedale.lecco.it


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