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Nephrol Dial Transplant (2001) 16: 56-60
© 2001 European Renal Association-European Dialysis and Transplant Association


Determinants of haemodialyser performance and the potential effect on clinical outcome

William R. Clark1,2, and Claudio Ronco3

1 Renal Division, Baxter Healthcare Corp., McGaw Park, IL, 2 Nephrology Division, Indiana University School of Medicine, Indianapolis, IN, USA and 3 Nephrology Division, Opsedale San Bortolo, Vicenza, Italy

Abstract

The performance of a dialyser is determined by several factors. Many of these factors relate to the dialyser membrane, including mean pore size, pore size distribution, wall thickness, surface area, and adsorptivity. In this article, several of these factors are reviewed. The potential impact of these factors on the clinical outcome of chronic haemodialysis patients is also discussed.

Keywords: convection; dialyser; flux; haemodialysis; membrane

Notes

Correspondence and offprint requests to: William R. Clark, Hemodialysis Research Laboratory, Renal Division, Baxter Healthcare Corporation, Wishard Hospital/Myers Building D711, 1001 West 10th Street, Indianapolis, IN 46202, USA.


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