Nephrol Dial Transplant (2001) 16: 1615-1619
© 2001 European Renal Association-European Dialysis and Transplant Association
Assessment of haematuria: automated urine flowmetry vs microscopy
1 Department of Medicine, 2 Department of Surgery and 3 Department of Clinical Chemistry, Rogaland Central Hospital, Stavanger, Norway
Background. Microscopy of the urine sediment may be a useful method in the distinction between a glomerular and a non-glomerular source of urinary bleeding. However, microscopic techniques are time consuming and hampered by inter-observer variations. In the present study we have therefore compared bright-field microscopy with automated urine flowmetry (SysmexTM UF-100), examining their ability to differentiate between glomerular and non-glomerular haematuria.
Methods. Fresh urine samples were obtained from 112 patients with a well-defined, single cause of a positive dipstick test. Their urine specimens were examined within 4 h in a blinded manner. Of them, 79 specimens had a positive dipstick for blood and thus could be evaluated for haematuria.
Results. The SysmexTM UF-100 had a sensitivity and specificity of 0.83 and 0.94 respectively in detecting non-glomerular bleeding. The positive and negative predictive values were 0.95 and 0.78 respectively. The corresponding values of microscopy were 0.79 and 0.90 respectively, and 0.93 and 0.74 respectively.
Conclusions. Automated flowmetry can be used in the distinction between glomerular and non-glomerular haematuria.
Keywords: glomerular; haematuria; non-glomerular; urine flowmetry; urine microscopy; urine sediment
Correspondence and offprint requests to: Terje Apeland, Medical Department, Rogaland Central Hospital, N-4011 Stavanger, Norway.
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