Nephrology Dialysis Transplantation, Vol 13, Issue 90008 26-29, Copyright © 1998 by Oxford University Press
A Zuccala, F Losinno, A Zucchelli and P Zucchelli
Background: Diabetes mellitus is an important cause of
end-stage renal failure (ESRF). Although classic diabetic nephropathy
accounts for the majority of patients reaching ESRF, renovascular disease,
which is frequent in such patients, plays an increasingly important role.
Percutaneous transluminal renal angioplasty (PTRA) has been proven to be an
efficacious measure for renal
revascularization.Methods: Ninety-nine patients with
diabetes mellitus and renal artery stenosis, corresponding to 16.6% of the
entire population of diabetic patients, were treated by PTRA or with the
Palmaz-Schatz stent in our clinic. Technical success was achieved by PTRA
in 92/99 patients, in 10 patients a Palmaz-Schatz stent was
implanted.Results: Hypertension was cured in eight and
improved in 44 patients. In 47 patients, there was no impact on blood
pressure. An improvement in renal function was evident 1 month after PTRA
in 8/27 patients. A further improvement occurred in another four patients
after 6 months. The re-stenosis rate was 22% after 5 years. Serious
complications occurred in seven patients (one patient required surgery and
two patients had regular dialysis
treatment).Conclusions: Renovascular disease is an
important cause of ESRF in diabetic patients. PTRA is a valid tool to
revascularize renal artery stenosis and improve blood pressure control and
renal function both in diabetic and non-diabetic patients.Key
words: diabetes mellitus; hypertension; intravascular stent;
percutaneous transluminal angioplasty; renal insufficiency; renovascular
disease
ORIGINAL ARTICLES
Renovascular disease in diabetes mellitus: treatment by percutaneous transluminal renal angioplasty
Divisone di Nefrologia e Dialisi Malpighi and Servizio di Radiologia, Policlinico S Orsola-Malpighi, Via P Palagi, 9, 40138 Bologna, Italy; Corresponding author
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  A. Karagiannis, K. Tziomalos, K. Dona, A. Pyrpasopoulou, N. Kartali, V. Athyros, and C. Zamboulis Bilateral renal artery stenosis and primary aldosteronism in a diabetic patient QJM, December 1, 2005; 98(12): 913 - 915. [Full Text] [PDF]
|
|
|
|
 |
|
 C. J Hay and P. A Kalra Review: Renovascular disease in diabetic patients The British Journal of Diabetes & Vascular Disease, March 1, 2002; 2(2): 91 - 95. [Abstract] [PDF]
|
|
|
|
 |
|
 N. Zerrenthin Relationship of renal dysfunction to proximal arterial disease severity in atherosclerotic renovascular disease Nephrol. Dial. Transplant., June 1, 2001; 16(6): 1300 - 1301. [Full Text] [PDF]
|
|