Nephrology Dialysis Transplantation, Vol 13, Issue 9 2261-2264, Copyright © 1998 by Oxford University Press
A Simon, P Lima, M Almerinda, V Alves, P Bottini and J de Faria
Background: In normal subjects, protein loading with
soybean meal does not produce the same renal haemodynamic effects as those
observed with a beefy meal. The renal responses of an acute protein load in
the form of chicken meal is unknown. Methods: To
examine whether the renal response to a chicken meal differs from that to
beef, we studied the renal function of eight normal healthy volunteers
before and after a protein load with each of these meals. In a crossover
randomized study, we measured the glomerular filtration rate (GFR; inulin
clearance), renal plasma flow (RPF; para-aminohippurate clearance and,
plasma amino acid and glucagon levels. We also determined the amino acid
content of a sample of chicken and beef. Results: GFR
and RPF increased significantly 2 h after both the chicken and beef meals
(chicken, 98±13 vs 119±18 and
476±123 vs 570±99 ml/min/1.73
m2; beef, 107±14 vs
122±16 and 501±118 vs
560±97 ml/min/1.73 m2, for GFR and RPF at
basal and 2 h respectively, P<0.05). Renal vascular resistance
decreased and the filtration fraction remained unchanged after both protein
loads. The changes induced by the protein challenges in the plasma amino
acid and glucagon levels were not different between the two protein
sources. The amino acid contents of chicken and beef samples were similar.
Conclusion: In normal subjects, chicken and beef meals
induced a similar degree of hyperfiltration. Key
words: beef; chicken; diabetic nephropathy; glomerular
hyperfiltration; protein load; renal haemodynamics
ORIGINAL ARTICLES
Renal haemodynamic responses to a chicken or beef meal in normal individuals
Renal Pathophysiology Laboratory, Nephrology Unit, Department of Internal Medicine, Faculty of Medical Sciences, State University of Campinas, Campinas, SP, Brazil; Corresponding author
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  K. Kalantarinia, J. T. Belcik, J. T. Patrie, and K. Wei Real-time measurement of renal blood flow in healthy subjects using contrast-enhanced ultrasound Am J Physiol Renal Physiol, October 1, 2009; 297(4): F1129 - F1134. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. T. Ndovi, Y.-J. Cao, E. Fuchs, C. V. Fletcher, A. Guidos, and C. W. Hendrix Food Affects Zidovudine Concentration Independent of Effects on Gastrointestinal Absorption J. Clin. Pharmacol., November 1, 2007; 47(11): 1366 - 1373. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Zitta, K. Stoschitzky, R. Zweiker, K. Oettl, G. Reibnegger, H. Holzer, and W. Estelberger Dynamic renal function testing by compartmental analysis: assessment of renal functional reserve in essential hypertension Nephrol. Dial. Transplant., August 1, 2000; 15(8): 1162 - 1169. [Abstract] [Full Text] [PDF]
|
|