Nephrology Dialysis Transplantation, Vol 13, Issue 6 1511-1517, Copyright © 1998 by Oxford University Press
A Johansson, O Samuelsson, B Haraldsson, I Bosaeus and P Attman
Background: Malnutrition is a common complication in
uremia and during maintenance dialysis. Several factors contribute to its
development. Different modes of dialysis treatment may differ in their
effects on nutritional status. Methods: In order to
analyse the nutritional consequences of peritoneal dialysis (PD), body
composition analyses were performed in PD patients between February 1993
and March 1996. Body cell mass (BCM) was estimated from measurements of
total body potassium (TBK) in a whole-body counter. Total body water (TBW)
was determined by measurement of tritiated water. Body fat (BF) was
calculated from body weight (BW), TBK and TBW. Observed values were related
to predicted (o/p) derived from local population studies.
Results: Sixty patients were repeatedly investigated
during the study period. Of these, 34 were investigated during the first
year of PD. At the start of dialysis, TBK o/p was 0.94 and BF o/p 0.76. No
change in body composition was seen during the observation period in the
group as a whole. However, within the group individual changes in BW were
strongly correlated with individual changes in BF (r=0.66, P=0.0001).
Twenty-six patients were examined during the second and third year of PD.
In this group, BW o/p remained constant over time. However, there was a
small but significant decline of TBK o/p and a concomitant increase of BF
o/p (P<0.05). No correlation was observed between changes in TBK and
changes in serum albumin. Conclusions: The results of
this study indicate, that there may be a risk for further reduction of body
cell mass during long-term PD treatment, while body energy stores are
maintained or even increased. Key words: body
composition; malnutrition; peritoneal dialysis; total body potassium; total
body water; body fat
ORIGINAL ARTICLES
Body composition in patients treated with peritoneal dialysis
Departments of Nephrology and Clinical Nutrition, Sahlgrenska University Hospital, S-413 45 Goteborg, Sweden; Corresponding author
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  K.-H. Cho, J.-Y. Do, J.-W. Park, and K.-W. Yoon Effect of icodextrin dialysis solution on body weight and fat accumulation over time in CAPD patients Nephrol. Dial. Transplant., September 19, 2009; (2009) gfp473v1. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Smith, B. Engel, A. M Diskin, P. Spanel, and S. J Davies Comparative measurements of total body water in healthy volunteers by online breath deuterium measurement and other near-subject methods Am. J. Clinical Nutrition, December 1, 2002; 76(6): 1295 - 1301. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Stenvinkel, O. Heimburger, B. Lindholm, G. A. Kaysen, and J. Bergstrom Are there two types of malnutrition in chronic renal failure? Evidence for relationships between malnutrition, inflammation and atherosclerosis (MIA syndrome) Nephrol. Dial. Transplant., July 1, 2000; 15(7): 953 - 960. [Full Text] [PDF]
|
|
|
|
 |
|
 P. STENVINKEL, B. LINDHOLM, F. LÖNNQVIST, K. KATZARSKI, and O. HEIMBÜRGER Increases in Serum Leptin Levels during Peritoneal Dialysis Are Associated with Inflammation and a Decrease in Lean Body Mass J. Am. Soc. Nephrol., July 1, 2000; 11(7): 1303 - 1309. [Abstract] [Full Text]
|
|