Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Thong, W.
Right arrow Articles by Nicol, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Thong, W.
Right arrow Articles by Nicol, D.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nephrol Dial Transplant (1995) 10: 2101-2103
© 1995 European Renal Association-European Dialysis and Transplant Association

research-article

Nephrogenic metaplasia: long-term haemodialysis and anuria as potential risk factors and reversibility with renal transplantation

W. Thong1, R. Hinsch1, A. Clouston2 and D. Nicol1,

1Department of Urology, Princess Alexandra Hospital Woolloongabba, Queensland, Australia 2Department of Pathology, Princess Alexandra Hospital Woolloongabba, Queensland, Australia

Correspondence and offprint requests to: Correspondence and offprint requests to: Dr D. Nicol, Director of Urology and Renal Transplantation, Princess Alexandra Hospital, Ipswich Rd, Woolloongabba, Queensland 4102, Australia

AIM.: To determine the incidence of nephrogenic metaplasia in patients with defunctionalized bladders due to long-term end-stage renal failure on haemodialysis.

METHODS.: From the dialysis registry of the Princess Alexandra Hospital 13 anuric patients who had been on haemodialysis for 10 or more years were identified. Of these, seven were currently awaiting renal transplantation and six had successful transplants. Endoscopic assessment of their lower urinary tracts was performed.

RESULTS.: Three cases of nephrogenic metaplasia were identified. In one case this led to significant haematuria following transplantation. However, the changes of nephrogenic metaplasia disappeared over the subsequent 18 months without specific treatment.

CONCLUSIONS.: It appears that a chronically defunctionalized bladder in the presence of end-stage renal failure is associated with an increased risk of nephrogenic metaplasia. These changes may spontaneously regress following transplantation and restoration of bladder function.

Keywords: bladder; dialysis; end-stage renal failure; nephrogenic metaplasia; nephrogenic adenoma


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.